New Evidence Shows Risk Begins Earlier Than Previously Thought
A major new study published in the Journal of Studies on Alcohol and Drugs is reshaping the conversation about alcohol and disease. The research shows that health risks linked to alcohol use begin at much lower levels than many people realise.
In fact, the study found that already one alcoholic beverage per day increases the risk of premature death from conditions directly caused by alcohol.
The Alcohol Intake and Health Study was originally commissioned to help inform the 2025–2030 U.S. Dietary Guidelines. Researchers from the United States and Canada reviewed more than 7,200 scientific studies and applied the findings to large U.S. health datasets to estimate the long-term health risks linked with different levels of alcohol use.
Their conclusion was clear: health risks begin with low-dose alcohol use and increase as alcohol consumption rises.
For example, the study found that the lifetime risk of death due to alcohol reaches one in 1,000 people at approximately seven alcoholic beverages per week. The risk rises dramatically with higher alcohol use. At 14 alcoholic beverages per week, researchers estimated a one-in-25 lifetime risk of death caused by alcohol.
Lead author Dr. Kevin Shield of the University of Toronto summarised the findings simply: even low levels of alcohol use come with health risks, and those risks continue to increase with greater alcohol consumption.
Alcohol Harm Extends Across Multiple Diseases
The study examined both chronic diseases and acute harms linked to alcohol use.
Researchers found increased risks for:
- Liver cirrhosis,
- Oral cancer,
- Esophageal cancer,
- Liver cancer,
- Breast cancer,
- Cardiovascular disease, and
- Injuries and injury-related deaths.
Women appeared to face particularly elevated risks for some conditions. For instance, women who consumed one alcoholic beverage per day showed increased risks of death from liver cancer and breast cancer compared with women who did not consume alcohol.
The researchers also found that consuming more than one alcoholic beverage on an occasion was linked with progressively higher risks of breast cancer, cardiovascular disease, and injury.
Importantly, the study found no significant overall protective health effect from alcohol at any level of consumption.
While some limited associations emerged between low-dose alcohol use and reduced risk of certain conditions, these findings did not outweigh the overall harms linked to alcohol use. However, when researchers considered the full range of alcohol-caused diseases and injuries, they concluded that alcohol’s risks outweighed any potential benefits.
Former Health Official Reveals Why Trump Buried Study
The publication of the study has attracted significant attention because the research was not incorporated into the latest U.S. Dietary Guidelines, reports Scientific American.
Robert Vincent, former Associate Administrator for Prevention and Treatment Policy at the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA), alleges that political and commercial pressure contributed to the study being sidelined.
In interviews and an accompanying editorial, Mr. Vincent explained that the study originated from concerns among public health agencies about rising alcohol harm and the need for updated scientific evidence to inform dietary guidance.
According to Mr. Vincent, an independent scientific review panel and a federal technical review subcommittee oversaw the study. The process included public consultation and external scientific scrutiny.
However, as the study neared completion, Mr. Vincent said opposition intensified. He reported receiving requests from people connected to the alcohol industry to terminate the project. He also described pressure from individuals inside government agencies who wanted the study halted. He said congressional inquiries, Freedom of Information Act requests, and subpoenas followed as criticism of the study increased.
The scientific review panel submitted its report in March 2025. According to Vincent, the new administration then largely ignored the findings. Mr. Vincent argues that people deserve clear scientific information about alcohol risks. He also emphasises that the evidence increasingly shows that risk begins with the first alcoholic beverage and that previous guidance allowing higher daily consumption no longer reflects the best available science.
HHS Responds to Widely Discussed Study Findings They Tried to Bury
The U.S. Department of Health and Human Services (HHS) disputes claims that the study was suppressed. Department spokesperson Emily Hilliard stated that officials reviewed the Alcohol Intake and Health Study alongside a broader body of scientific evidence during development of the 2025–2030 Dietary Guidelines. According to HHS, the dietary guidelines relied on the totality of scientific evidence rather than any single report.
The final guidelines abandoned the long-standing recommendation of up to two alcoholic beverages per day for men and one for women. Instead, they advise U.S. Americans to consume less alcohol for better overall health.
Researchers involved in the Alcohol Intake and Health Study argue that this guidance remains too vague because it does not identify the level at which alcohol risks begin to increase. The study’s authors concluded that adults who consume alcohol should limit intake to one alcoholic beverage or less per day, based on the evidence they reviewed.
Why Different Reviews Reached Different Conclusions
A major source of controversy involves another review conducted by the National Academies of Sciences, Engineering and Medicine (NASEM). The NASEM review, cited in the New York Times, suggested that moderate alcohol use was linked with lower all-cause mortality, although it also identified an increased risk of breast cancer.
Researchers behind the Alcohol Intake and Health Study used a different approach. Instead of examining all causes of death, they focused specifically on diseases and injuries known to be caused by alcohol. This included cancers, liver disease, cardiovascular conditions, and injuries.
Critics of the NASEM review argue that studies of moderate alcohol consumers can be influenced by factors unrelated to alcohol, such as income, healthcare access, diet, and other lifestyle behaviours.
The Alcohol Intake and Health Study sought to isolate alcohol-specific risks using U.S. population data and modeling techniques. Even researchers involved in the NASEM review agreed on one point. Dr. Ned Calonge, who led the NASEM study, stated that he does not believe anyone should begin consuming alcohol for health reasons.
Concerns About Industry Interference
Long before publication of the study, Movendi International highlighted concerns about alcohol industry interference in the U.S. guideline development process.
In October 2024, reporting documented how approximately 100 members of the U.S. Congress called on the Department of Health and Human Services to suspend the Alcohol Intake and Health Study. The lawmakers did the dirty work on behalf of the alcohol industry, claiming that the study duplicated a separate review conducted by the National Academies. Public health experts questioned those claims and pressures and raised concerns about alcohol industry lobbying around the dietary guidelines process.
The reporting also highlighted previous examples of alcohol industry interference. For example, Distilled Spirits Council lobbying expenditures exceeded $4 million in 2015 during earlier debates over U.S. dietary guidelines.
Ten years later, in September 2025, additional reporting highlighted concerns that the Alcohol Intake and Health Study had been excluded from policymaking despite findings showing elevated risks from low-dose alcohol use, increased cancer risk, and substantial years of life lost due to alcohol-caused deaths.
The debate surrounding the study illustrates a broader challenge facing health policy worldwide: ensuring that scientific evidence about alcohol harm reaches the politicians and people without interference from commercial interests.
What This Means for Public Health
The findings of the JSAD study add to growing international evidence showing that alcohol use carries health risks already at low levels.
For example, the study found that alcohol use increases the risk of cancers, liver disease, cardiovascular disease, injuries, and premature death. In fact, researchers did not identify any level of alcohol use that produced a significant overall health benefit once all alcohol-caused harms were considered.
The publication of the Alcohol Intake and Health Study is likely to continue influencing discussions about health promotion, evidence-based alcohol policy, and the people’s right to accurate information about alcohol harm.
As scientific understanding evolves, the evidence increasingly points in one direction: preventing and reducing alcohol use promotes better health and lowers the risk of serious disease and premature death.
Sources
The New York Times: “Health Risks of Alcohol Accelerate After One Drink a Day, Study Finds”
STAT News: “Alcohol study discarded by Trump officials is published in scientific journal”
Yahoo! News: “Former U.S. health official explains why Trump administration buried alcohol study”
Scientific American: “Former U.S. Health Official Explains Why the Trump Administration Ignored a Key Alcohol Study“
STAT News: “HHS responds to paper on alcohol risk that Trump administration sought to bury”
The Hill: “New study on alcohol risks adds fuel to debate over U.S. drinking guidelines”
NBC News: “No amount of alcohol is safe, a team of scientists says“
Journal of Studies on Alcohol and Drugs (JSAD): “Alcohol Intake and Health Study“
Movendi International: “White House and Industry Allies Suppress Landmark Study on Alcohol and Cancer“
Movendi International: “Exposed: Some U.S. Congress Members Interfere Against Independent Alcohol Research”