This study aimed to provide up-to-date and comprehensive estimates on the global alcohol cardiomyopathy (ACM) from 1990 to 2019.
The absolute number of prevalent cases, DALYs cases and deaths due to alcohol cardiomyopathy significantly increased between 1990 and 2019. ACM remains an important global public health concern.

Author

Xin-Jiang Dong, Bei-Bei Wang, Yang Jiao, Fei-Fei Hou, Xiao-Qi Zhang

Citation

Dong XJ, Wang BB, Jiao Y, Hou FF, Zhang XQ. Global, regional and national burden of alcohol cardiomyopathy from Global Burden of Disease Study 2019. Intern Emerg Med. 2023 Feb 14. doi: 10.1007/s11739-023-03204-z. Epub ahead of print. PMID: 36786978.

Source
Internal and Emergency Medicine
Release date
14/02/2023

Global, regional and national burden of alcohol cardiomyopathy from Global Burden of Disease Study 2019

Original paper

Abstract

Aim

This study aimed to provide up-to-date and comprehensive estimates on the global alcohol cardiomyopathy (ACM) from 1990 to 2019.

Definition

Alcoholic cardiomyopathy is a disease in which the chronic long-term use of alcohol (i.e., ethanol) leads to heart failure, according to Wikipedia. Alcoholic cardiomyopathy is a type of dilated cardiomyopathy. Due to the direct toxic effects of alcohol on heart muscle, the heart is unable to pump blood efficiently, leading to heart failure. It can affect other parts of the body if the heart failure is severe. It is most common in males between the ages of 35 and 50.

Method

Detailed data on the prevalence, disability-adjusted life-years (DALYs), deaths, percentage change in the number of cases and estimated annual percentage change (EAPC) of alcohol cardiomyopathy worldwide from 1990 to 2019 were obtained or calculated from the Global Burden of Disease Study (GBD) 2019.

Results

Globally, the estimated prevalent cases of alcohol cardiomyopathy in 2019 were 707,652, with a 35.4% increase from 522,616 in 1990.

35%
3 Decades rise in alcohol cardiomyopathy
Between 1990 and 2019, cases of alcohol cardiomyopathy rose from 522,616 to 707,652. This is a 35.4% increase in cases of global alcohol cardiomyopathy.

The age-standardized prevalence rate (ASPR) was slightly decreased with an overall annual percentage change of – 1.30. Similar to ASPR, the global age-standardized DALYs rate and age-standardized death rate (ASDR) also declined, with an EAPC of – 1.12 and – 1.53 from 1990 to 2019, respectively.

Conversely, the number of ACM-related DALYs cases in 2019 was 2,441,108, with an increase of 38.8% over the past 30 years, and the number of ACM-related deaths in 2019 was 71,723, with an increase of 33.1% compared with 1990.

39%
Increase in disability-adjusted life-years due to alcohol cardiomyopathy
The number of ACM-related DALYs cases in 2019 was 2,441,108, with an increase of 38.8% over the past 30 years.

A significant variation in the burden of ACM was observed between different regions and countries.

Conclusion

Although the ASPR, age-standardized DALYs rate and ASDR slightly decreased from 1990 to 2019, the absolute number of prevalent cases, DALYs cases and deaths significantly increased.

This showed that the burden of ACM remains an important global public health concern.

Public health policy and decision-makers should develop and implement more effective strategies specific to geographical location to combat and reduce the burden of ACM in the future.

Source Website: Springer Medizin